What drug may need to be added to a patient's medication list when starting tazemetostat?

When considering the use of tazemetostat, particularly in treating certain malignancies such as epithelioid sarcoma and follicular lymphoma, it’s important to recognize potential interactions and the need for supportive medications. Tazemetostat is an EZH2 inhibitor, which can potentially lead to neurological and psychiatric side effects, including anxiety and sleep disturbances.

Prochlorperazine, an antipsychotic and antiemetic, can be beneficial in managing these side effects. It can help relieve symptoms of nausea and anxiety that may arise in patients undergoing cancer treatment, providing a supportive role alongside the primary therapy. This adjunctive use can improve the overall well-being of the patient as they navigate the side effects associated with tazemetostat.

In contrast, while aspirin may be used for various reasons, it does not specifically aid in the management of tazemetostat-related side effects. Calcium carbonate serves mainly as an antacid and does not relate directly to the side effects of tazemetostat. Phenytoin, an anticonvulsant, is also not indicated in this context as it does not address the primary concerns that may arise with tazemetostat treatment.

Given this context, the addition of prochlorperazine to a