Identify the application developed to assist clinicians in optimizing pharmacological therapy for patients with chronic stage C HFrEF.

The application developed specifically to assist clinicians in optimizing pharmacological therapy for patients with chronic stage C Heart Failure with reduced ejection fraction (HFrEF) is TreatHF. This tool provides evidence-based guidance tailored for managing heart failure, focusing on improving medication regimens and monitoring patient outcomes. It integrates clinical guidelines and research to help healthcare professionals make informed decisions about treatment options, thereby enhancing patient care.

The other applications mentioned serve different purposes or target different aspects of heart failure management, making them less suitable for this specific scenario. HF Guide and HF Path, while useful in the broader context of heart failure management, are not as directly aligned with the optimization of pharmacological therapy in stage C HFrEF as TreatHF is.