Depression may occur at what stage in patients with Parkinson's disease?

Depression is recognized as a common non-motor symptom of Parkinson's disease, and it can manifest at various points in the disease progression. Research indicates that depressive symptoms can occur even before the characteristic motor symptoms are present, as well as throughout the course of the illness, regardless of the stage. This highlights the complexity of Parkinson's disease, where neurobiological changes associated with the condition can lead to mood disorders.

Additionally, depression can appear early in the disease process, sometimes as a reaction to the diagnosis of Parkinson's, or as part of the overall burden of living with a chronic illness. This dynamic underscores the importance of monitoring mental health continuously in patients with Parkinson's, as early intervention for depression can improve overall quality of life.

Therefore, the assertion that depression may occur at any stage before or after a diagnosis of Parkinson's disease is well-supported by clinical observations and research findings.